PhD Structural Biology: The University of Manchester

Course description

PhD programmes are based on individual research projects that last 3 or 4 years, working with a specific academic supervisor (principle investigators). Applicants are specifically matched with a principle investigator based on their research interests and background.

Activity in the Structural Biology, Enzymology and Biophysics group spans across four major themes: biocatalysts (enzymes), membrane proteins, RNA protein interactions and the extracellular matrix. At Manchester they aim to take a holistic and integrated approach to research activity in these areas, providing a hub for detailed molecular analysis of biomolecular structure and function within the Faculty. There are strong interdisciplinary links with other themed areas in the Faculty, and other Schools and research institutes in the University. Infrastructure within the group is superb and includes state-of-the-art crystallisation robots, X-ray generators, computational and NMR facilities. The group also has unique facilities for advanced spectroscopy, fast reaction methods and computational infrastructure. The group is part of a large consortium that has received substantial funding (£6.8 million) to study membrane protein structure. A national centre for the robotic evolution of enzymes was established recently in the group through substantial funding (£2.2 million) from BBSRC.

Career opportunities

In terms of career progression, the majority of their postgraduate students remain in research, while others move into related areas such as education, information technology, consultancy and management, helped by the  comprehensive skills training they gain during their programme of study.

Entry requirements

Academic entry qualification overview:

The standard entry requirement for PhD study is a First or Upper Second class honours degree, or the overseas equivalent, in a relevant subject. In certain circumstances, a Lower Second class honours degree supplemented by a Masters degree, or appropriate relevant work experience, may be acceptable.

English language:

For PhD applicants whose first language is not English an IELTS score of 6.5, TOEFL 577 (paper based), TOEFL 233 (computer based) or TOEFL 90 (internet based) is required as a minimum.