k...@mole.bio.cam.ac.uk
The laboratories of the Department of Clinical Biochemistry are located in the Institute of Metabolic Science (IMS) and in the Cambridge Institute for Medical Research (CIMR). The energies of the Department are focused very strongly on research, and each year we receive over £4 million in grants from UK Research Councils, medical charities and industry. We believe this substantial financial support reflects our international reputation in our key research areas. There is a strong commitment to progressing the careers of young scientists. Many of our PhD students go on to postdoctoral work in the UK, elsewhere in Europe, or in the USA, while others elect to pursue opportunities in industry or the financial sector.
Research is focused in two areas:
Interests include the genetics and biochemistry of obesity and insulin resistance (Prof S O'Rahilly, Dr A Vidal-Puig. Dr S Farooqi, Dr D Savage); adipogenesis (Prof S O'Rahilly, Dr A Vidal-Puig); receptors and signalling pathways mediating actions of insulin and IGFs (Prof K Siddle); the role of fetal nutrition in programming adult metabolism and disease (Dr S Ozanne); structure and function of ion channels involved in the regulation of endocrine secretion (Dr F Gribble).
Interests include sorting and fusion mechanisms on membrane traffic pathways (Prof JP Luzio, Dr A Peden); vesicle coats and adaptor proteins (Prof MS Robinson); structural biology of traffic proteins (Dr D Owen); myosin motor proteins in membrane traffic (Dr F Buss); nuclear membrane biogenesis (Dr S Siniossoglou).
There are close links with other departments in the Clinical School, especially within the Institute of Metabolic Science (IMS) and Cambridge Institute for Medical Research (CIMR), and also with departments in the School of Biological Sciences, especially Physiology and Biochemistry.
Enquiries: Projects in Diabetes and Obesity (Institute of Metabolic Science) Prof K Siddle
Enquiries: Projects in Molecular Cell Biology of Membrane Traffic (Cambridge Institute for Medical Research) Prof JP Luzio
Further information: