PhD Neuroscience (Life Sciences): The University of Manchester

Course description

PhD programmes are based on individual research projects that last 3 or 4 years, working with a specific academic supervisor (principle investigators). Applicants are specifically matched with a principle investigator based on their research interests and background.

Neuroscientists in the Faculty interact to deliver a wide range of projects focused on research into the cellular and molecular mechanisms of neuronal regulation and neurodegeneration in the CNS and PNS. A major focus is to understand processes of neurodegeneration in order to uncover aetiology and/or treat the common diseases of the nervous system, for example Alzheimers, Parkinsons disease and stroke. There are also several groups studying how the brain controls complex behaviours such as feeding and sleeping. In vivo and in vitro techniques are used and include primary neuronal cell culture, patch-clamp recording, ion flux Imaging, receptor binding assays and imaging of GFP- fusion proteins. There is a significant level of collaboration with clinicians and major links with large and small pharmaceutical companies. Drug discovery programmes and neuroscience- based spin out companies are being set up and encouraged through interaction with Manchester Biotech, which is ideally positioned adjacent to the Faculty.

General areas of neuroscience research include:

• The Basal Ganglia & Movement Disorders
• Actions of Cytokines & Growth Factors in the Brain
• Cell Biology of Neuronal Regulation & Neurodegeneration
• Molecular Basis of Ion Channel Function
• Peripheral & Diabetic Neuropathy
• Comparative Neuroendocrinology
• Neuronal Control of Biological Clocks
• Regulation of Body Weight & Feeding

Career opportunities

In terms of career progression, the majority of their postgraduate students remain in research, while others move into related areas such as education, information technology, consultancy and management, helped by the  comprehensive skills training they gain during their programme of study.

Entry requirements

Academic entry qualification overview:

The standard entry requirement for PhD study is a First or Upper Second class honours degree, or the overseas equivalent, in a relevant subject. In certain circumstances, a Lower Second class honours degree supplemented by a Masters degree, or appropriate relevant work experience, may be acceptable.

English language:

For PhD applicants whose first language is not English an IELTS score of 6.5, TOEFL 577 (paper based), TOEFL 233 (computer based) or TOEFL 90 (internet based) is required as a minimum.